Load reduction in live PRRS vaccines using oil and polymer adjuvants
نویسندگان
چکیده
منابع مشابه
Compilation of experimental investigations of PRRS vaccine technologies using modified live vaccines, inactivated vaccines and immunomodulation
Numerous vaccine and control tools have been introduced to the marketplace including licensed modified live PRRS vaccines (MLV), licensed inactivated PRRS vaccines (KV), autogenous KV vaccines, and use of virulent live virus exposure (LVI). Based on published data and controlled experimental studies, the licensed MLV clearly provide the current gold standard of protection in respiratory and rep...
متن کاملNovel Adjuvants for Vaccines
The review covers basic recent discoveries on the mechanism of action of adjuvants, which have been developed in the last decade. In particular, it focuses on the activation of TOLL like receptors and subsequent release of pro-inflammatory lymphokines (innate immunity), which, in turn, are thought to activate antigen specific responses (adaptive immunity). Given the number of novel adjuvants av...
متن کاملAdjuvants, Preservatives and Tissue Fixatives in Vaccines
ADJUVANTS, PRESERVATIVES AND TISSUE FIXATIVES IN VACCINES V contain a number of substances which can be divided into the following groups: 1. Micro-organisms, either bacteria or viruses, thought to be causing certain infectious diseases and which the vaccine is supposed to prevent. These are whole-cell proteins or just the broken-cell protein envelopes, and are called antigens. 2. Chemical subs...
متن کاملBeyond antigens and adjuvants: formulating future vaccines.
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has motivated studies of the formulation of vaccines to control how, when, and where antigens and adjuvants encounter immune cells and other cells/tissues following administration. An effective subunit vaccine must traffic to lymph nodes (LNs), activate both the innate and adaptive arms of the immune system, an...
متن کاملAdjuvants in Immunization with Influenza Virus Vaccines
Subcutaneous inoculation, of PR8 allantoic fluid, or watery suspensions of the virus obtained from allantoic fluid by high-speed centrifugation or by elution after adsorption on red cells induced serum antibodies in experimental animals, which reached the highest levels within 2 weeks after inoculation and were gradually lost thereafter. The addition of killed acid-fast bacteria (Myco. tubercul...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Procedia in Vaccinology
سال: 2012
ISSN: 1877-282X
DOI: 10.1016/j.provac.2012.04.018